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Absorption, Pharmacokinetics and Disposition of Biodegradable Nanoscale Preparations

[ Vol. 13 , Issue. 4 ]

Author(s):

Cheng Wang, Jing Wang, Tiezhu Chen, Zhiqiang Luo, Xuemei Yang, Xiongfei Pan, Yunfeng Lin, Zhiyong Qian and Xiaoxiao Cai   Pages 429 - 439 ( 11 )

Abstract:


Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. This article aims to review the absorption, pharmacokinetics, distribution properties and toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.

Keywords:

Liposomes, micelles, nanoparticles, PLGA, SLN, passive targeting, active targeting

Affiliation:

State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, No.14., 3rd Sec, Ren Min Nan Road, Chengdu 610041, P.R. China.



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