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Deciphering the Role of Nanoparticle-Based Treatment for Parkinson’s Disease

Author(s):

Md. Marufur Rahman Moni, Mst. Marium Begum, Md. Sahab Uddin* and Ghulam Md Ashraf*   Pages 1 - 11 ( 11 )

Abstract:


Parkinson’s disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on our society. The occurrence of this neurodegenerative disease has been aggregating day-by-day. This disease can be a serious concern if the patients are left untreated. However, conventional treatment has many side-effects and less bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations. Nanotechnology has been introduced to us to deliver smart solutions to these circumstances. Nanotechnology has developed to provide efficient therapies that have reduced side-effects and have increased bioavailability in the brain. This review emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches. Besides, the advantages of different approaches on nanotechnology platforms are far better over conventional therapy in the treatment of Parkinson’s disease.

Keywords:

Parkinson's disease, Progressive neurodegenerative disorder, Nanotechnology, Nanoparticles, α-synuclein, Bloodbrain barrier

Affiliation:

Department of Pharmacy, East West University, Dhaka, Department of Pharmacy, East West University, Dhaka, Department of Pharmacy, Southeast University, Dhaka, King Fahd Medical Research Center, King Abdulaziz University, Jeddah



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